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Jennifer Doudna
Biochemist

Jennifer Doudna

Famoose for

Co-developing CRISPR-Cas9 as a programmable tool for editing DNA.

CRISPR-Cas9 · Nobel Prize 2020

Born
19 February 1964
Birthplace
Washington, D.C., United States

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Jennifer Doudna

Jennifer Doudna is an American biochemist whose collaboration with Emmanuelle Charpentier produced a method for precisely cutting DNA. They shared the 2020 Nobel Prize in Chemistry.

Early life

Hawaii childhood

Grew up in Hilo, where the natural world helped spark her interest in science.

Chemistry training

Studied at Pomona College and completed a doctorate at Harvard under Jack Szostak.

Career

  1. 1994

    Yale laboratory

    Established research on RNA structure and function.

  2. 2002

    Berkeley move

    Joined the University of California, Berkeley.

  3. 2012

    Programmable DNA cutting

    Published the CRISPR-Cas9 work with Charpentier and their collaborators.

  4. 2020

    Chemistry Nobel

    Shared the prize for developing a genome-editing method.

Contributions

RNA structures

Investigated how RNA folds and carries out chemical reactions.

CRISPR-Cas9 method

Showed that an RNA guide could direct Cas9 to cut a chosen DNA sequence.

A Crack in Creation

Co-wrote a book with Samuel Sternberg about gene editing and its implications.

Beyond the lab

Ethical questions

Has called for public discussion of the consequences of editing human embryos and inherited DNA.

Research into applications

Co-founded the Innovative Genomics Institute, pursuing uses of genome editing in health and agriculture.

Sources & photo creditLife, career and referencesNobel Prize biography and award

Photo: Christopher Michel. CC BY-SA 4.0 · Original image. Cropped and displayed in monochrome.