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Martin Chalfie
Biologist

Martin Chalfie

Famoose for

Showing how green fluorescent protein could mark living cells for scientific study.

Touch circuitry · Glowing cells

Born
15 January 1947
Birthplace
Chicago, United States

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Martin Chalfie

Martin Chalfie is an American biologist who shared the 2008 chemistry Nobel with Osamu Shimomura and Roger Tsien.

Early life

Chicago childhood

Grew up with a guitarist father and a mother who ran an apparel business.

Harvard

Studied biochemistry, then returned for doctoral research after temporary jobs.

Career

  1. 1977

    Doctorate

    Completed his Harvard PhD.

  2. 1982

    Columbia faculty

    Established a research programme on the nervous system of C. elegans.

  3. 1994

    GFP paper

    Published the demonstration of GFP as a genetic marker.

Contributions

Touch circuitry

Co-authored work mapping the worm’s touch-sensitive neural circuit.

Glowing cells

Demonstrated GFP expression in bacteria and nematodes.

Mechanosensation

Investigated how cells detect physical force.

Beyond the lab

Swimming

Captained Harvard’s swimming team as an undergraduate.

Family

Married fellow scientist Tulle Hazelrigg.

Sources & photo creditBiography and careerFurther source

Photo: Duncan.Hull. CC BY-SA 4.0 · Original image. Cropped and displayed in monochrome.