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Dorothy Hodgkin
Chemist

Dorothy Hodgkin

Famoose for

Using X-rays to reveal the structures of penicillin, vitamin B12 and insulin.

Penicillin · Insulin

Born
12 May 1910
Birthplace
Cairo, Egypt
Died
29 July 1994

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Dorothy Hodgkin

Dorothy Hodgkin was a British chemist who used crystallography to determine the shapes of complex biological molecules. She received the 1964 Nobel Prize in Chemistry.

Early life

Archaeology and crystals

Born to parents involved in archaeology and education, she developed an interest in crystals as a child.

Oxford and Cambridge

Studied chemistry at Somerville College, Oxford, then conducted doctoral research with J. D. Bernal at Cambridge.

Career

  1. 1934

    Oxford research

    Returned to Oxford and built a career studying biological molecules with X-rays.

  2. 1940s–1950s

    Complex structures

    Her group worked out structures including penicillin and vitamin B12.

  3. 1964

    Chemistry Nobel

    Received the prize for determining important biochemical structures.

  4. 1969

    Insulin solved

    Her team established insulin’s structure after decades of work.

Contributions

Penicillin

Clarified the structure of an important antibiotic.

Vitamin B12

Solved a molecule far more complex than many previous crystallographic targets.

Insulin

Revealed the three-dimensional structure of the hormone.

Beyond the lab

Living with arthritis

Developed rheumatoid arthritis as a young adult and continued her laboratory career despite its effects.

Peace advocacy

Served as president of the Pugwash Conferences, supporting dialogue over nuclear weapons and international security.

Sources & photo creditLife, career and referencesNobel Prize biography and award

Photo: University of Bristol. CC BY-SA 2.5 · Original image. Cropped and displayed in monochrome.