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Carolyn Bertozzi
Chemist

Carolyn Bertozzi

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Developing chemical reactions that can work inside living systems without disrupting their normal chemistry.

Bioorthogonal chemistry · Glycan imaging

Born
10 October 1966
Birthplace
Boston, Massachusetts, United States

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Carolyn Bertozzi

Carolyn Bertozzi is an American chemist whose research connects chemistry and cell biology. Her bioorthogonal methods let scientists label and track biological molecules in living systems. She shared the 2022 chemistry Nobel with Morten Meldal and K. Barry Sharpless.

Early life

Scientific surroundings

Grew up in Massachusetts in a family with a strong interest in science.

Harvard and Berkeley

Studied chemistry at Harvard and completed her doctorate at Berkeley in 1993.

Career

  1. 1996

    Berkeley faculty

    Started a research group studying the chemistry of sugars on cells.

  2. 2000s

    Bioorthogonal tools

    Developed reactions suitable for following biological processes in living systems.

  3. 2015

    Moving to Stanford

    Joined Stanford after leading a research group at Berkeley.

  4. 2022

    Nobel recognition

    Shared the Nobel Prize in Chemistry for click and bioorthogonal chemistry.

Contributions

Bioorthogonal chemistry

Created tools that react with selected targets without interfering broadly with cell chemistry.

Glycan imaging

Used chemical labelling to study sugars on cell surfaces.

Disease-focused chemistry

Extended these approaches towards understanding cancer and developing targeted treatments.

Beyond the lab

Music

Played keyboards in bands while studying at Harvard.

Inclusive laboratories

Has spoken about exclusion she encountered as a student and the importance of welcoming research environments.

Sources & photo creditLife, career and referencesInstitutional biography and career record

Photo: Christopher Michel. CC BY-SA 4.0 · Original image. Cropped and displayed in monochrome.