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Hugh Huxley
Biophysicist

Hugh Huxley

Famoose for

The sliding-filament explanation of muscle contraction.

Sliding-filament theory

Born
25 February 1924
Birthplace
Birkenhead
Died
25 July 2013

More people

Hugh Huxley

British researcher who used X-rays and electron microscopy to investigate the molecular machinery of muscle.

Early life

Physics and radar

Studied at Cambridge, interrupted his education for Royal Air Force radar work, then completed his degree in 1948 and doctorate in 1952.

Career

  1. 1950s

    MIT research

    Worked with Jean Hanson on the structure of muscle.

  2. 1954

    Sliding filaments

    Proposed how overlapping protein filaments produce contraction.

  3. 1969

    Cross-bridge model

    Developed a molecular account of force generation.

  4. 1987–1997

    Brandeis

    Held a professorship in Massachusetts.

Contributions

Sliding-filament theory

Showed that contraction involves movement of filaments past one another.

Beyond work

Wartime engineering

His work developing radar equipment earned an MBE and supplied practical skills used throughout his research.

Sources & photo creditBiography and careerBiographical references

Original photograph. Cropped and displayed in monochrome.

Photo: unknown. Source credit retained; reuse licence not established · Original image. Cropped and displayed in monochrome.