Contents
Paul Greengard
Revealing how chemical signals change the activity of nerve cells.
Protein phosphorylation · DARPP-32
- Born
- 11 December 1925
- Birthplace
- United States
- Died
- 13 April 2019
More people
Paul Greengard
Paul Greengard was a neuroscientist who studied the molecular mechanisms behind communication in the brain. He shared the 2000 Nobel Prize in Physiology or Medicine with Arvid Carlsson and Eric Kandel.
Early life
New York
Grew up in New York; his mother died when he was born.
Education
Studied mathematics and physics at Hamilton College before moving into biophysics.
Career
- 1953
Doctorate
Completed his PhD at Johns Hopkins.
- 1968
Yale
Began a professorship investigating nerve signalling.
- 1983
Rockefeller
Moved his laboratory to Rockefeller University.
- 2000
Nobel Prize
Was honoured for discoveries in nervous-system signalling.
Scientific work
Protein phosphorylation
Investigated how chemical changes regulate nerve-cell proteins.
DARPP-32
His laboratory studied a key protein involved in dopamine signalling.
Beyond work
Values
Turned away from theoretical physics partly because he did not want to contribute to nuclear weapons research.
Family
Married sculptor Ursula von Rydingsvard in 1985.
Sources & photo credit
Life, career and references ↗Biography and career evidence ↗Photo: See source. Public domain · Original image. Cropped and displayed in monochrome.
